Prana Doctors come across many people who take Azithral or any brand of Azithromycin over the counter antibiotic, when they have sore throat, cold cough. While it might have helped you on numerous occasions, the risks and benefits vary according the age and other co-morbidities the person has.
We highlight below the risk and benefits associated with taking Azithromycin.
Azithromycin is an important antibiotic used by Pulmonologists, ENT specialists, General Practitioners and other doctors.
It is used in
1. Community acquired pneumonia
2. Acute bacterial exacerbations of chronic obstructive pulmonary disease.
3. Uncomplicated skin and skin structure infections.
4. Genitourinary tract infections
In Pediatric :
Acute otitis media, Pharyngitis and Tonsiliitis.
Dosage:
Side-effects:
1. Diarrhoea/loose stools (4-5%)
2. Abdominal pain (2-3%)
3.Nausea (3-4%)
4. Vomiting (1%)
Azithromycin has had a recent label change which warrants this writing.
The revised label advises against the use of azithromycin in patients with known risk for QT interval prolongation, hypokalemia, hypomagnesemia, bradycardia.
This label revision is because of post marketing surveillance findings, an observational study involving Tennessee Medicaid Patients and also Danish national healthcare data.
Excerpts"
“For every 21,000 outpatient prescriptions written for azithromycin, one cardiovascular death occurred in excess of those observed with the same number of amoxicillin prescriptions. The excess risk over amoxicillin varied considerably according to cardiovascular risk factors; the researchers estimated that there was one excess cardiovascular death per 4100 prescriptions among patients at high cardiovascular risk but less than one per 100,000 among patients with lower cardiovascular risk.”
“The risks and benefits of antibacterial therapy should be considered in prescribing decisions. Pharmacologic and epidemiologic data point to lethal arrhythmias as a potential consequence of QT-interval prolongation with use of azithromycin, other macrolides, and fluoroquinolones. This possibility should give clinicians pause when they're considering prescribing antibacterial drugs, especially for patients with preexisting cardiovascular risk factors or clinical conditions in which antibacterial drug therapy has limited benefits.”
Cardiovascular Risks with Azithromycin and Other Antibacterial Drugs
N Engl J Med 2013; 368:1665-1668May 2, 2013DOI: 10.1056/NEJMp1302726
Prana Healthcare provides the general physician support as and when you need. Prana is you trusted "family doctor".
Prana Healthcare is a new age, compassionate, caring, primary healthcare provider. We send doctors for home visits and run primary care clinics in Bangalore.
Prana Healthcare provides the general physician support as and when you need. Prana is you trusted "family doctor".
Prana Healthcare is a new age, compassionate, caring, primary healthcare provider. We send doctors for home visits and run primary care clinics in Bangalore.
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